CT20p is an anticancer peptide derived from the hydrophobic terminal of BaxC. It exhibits a unique cytotoxic effect independent of the full-length Bax, targeting mitochondria to induce fusion-like aggregation and mitochondrial membrane hyperpolarization. CT20p reduces alpha5beta1 integrin levels, inhibits F-actin polymerization, thus disrupting the cytoskeleton and preventing cell adhesion. CT20p is applicable in breast cancer research.
Molecular Weight:
2176.66
CAS Number:
[1407967-57-0]
Formula:
C103H170N24O25S
Target:
Bcl-2 Family
TP3680
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