FNIII14 is derived from the 14th type III-like (FN-III) repeat sequence of the fibronectin (FN) molecule. It inhibits cellular adhesion to the extracellular matrix (ECM) by inducing beta1-integrin (beta1integrin) to shift from an active to an inactive state, blocking integrin-mediated signaling. With its antifibrotic and anticancer properties, FNIII14 is useful for research in metabolic diseases, organ fibrosis, and malignancies.
Molecular Weight:
2255.52
CAS Number:
[206536-96-1]
Formula:
C103H163N21O35
Target:
Integrin
TP3704
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