CIGB-552 is a cell-penetrating peptide with antitumor properties, exhibiting an IC50 of 23 µM in H460 cells. It increases the level of COMMD1 protein and significantly inhibits the NF-kappaB signaling pathway. Furthermore, CIGB-552 promotes apoptosis (apoptosis) of tumor cells and induces accumulation of reactive oxygen species (ROS) within them. Additionally, it possesses anti-inflammatory and anti-angiogenic effects. CIGB-552 is applicable in research related to lung and colon cancer.
Molecular Weight:
2689.21
CAS Number:
[1630763-23-3]
Formula:
C131H198N38O24
Target:
NF-kappaB|||Apoptosis|||ROS
TP3708
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