TpD is a chimeric T-helper epitope that features a specific site for cleavage by caspases. Immunization with TpD induces a strong antibody response and enhances long-term CD4 immune reactions in both animals and humans. It effectively binds to various human MHCII types, primarily HLA-DRB1, and also interacts with other HLA alleles, including DRB3, DRB4, DRB5, DP, and DQ. TpD can be utilized to amplify the immune response in peptide vaccines.
Molecular Weight:
3464.21
CAS Number:
[1273551-45-3]
Formula:
C158H264N38O42S3
Target:
MHC
TP3932
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