Apoptin-derived peptide acetate is an anticancer polypeptide with cytotoxic properties. It promotes apoptosis and necrosis in gastric cancer cells by modulating PI3K/AKT/ARNT signaling. Within cells, Apoptin-derived peptide acetate inhibits cancer cell invasion and migration and reduces the expression and phosphorylation of the PI3K subunit p85, thereby further inhibiting the PI3K/AKT pathway involved in gastric cancer progression.
Target:
Akt|||Apoptosis|||Necroptosis|||PI3K
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