FITC-Acp-RpYTPEP-NH2 is a potent fluorescent tracer. It exhibits binding affinity for the Cbl-b SH2 domain (Kd = 0.07 µM). Fluorescence polarization assays utilizing FITC-Acp-RpYTPEP-NH2 can be employed to assess inhibitors of the Cbl-b SH2 domain.
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E1/E2/E3 Enzyme
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