Rosiptor is a potent and selective SHIP1 activator. AQX-1125 inhibits Akt phosphorylation in SHIP1-proficient but not in SHIP1-deficient cells, reduces cytokine production in splenocytes, inhibits the activation of mast cells and inhibits human leukocyte chemotaxis. AQX-1125 suppresses leukocyte accumulation and inflammatory mediator release in rodent models of pulmonary inflammation and allergy.
Molecular Weight:
381.55
CAS Number:
[782487-29-0]
Formula:
C22H39NO4
Target:
Others|||Phosphatase
TQ0032L
* VAT and and shipping costs not included. Errors and price changes excepted
