Mal-PEG-OH (MW 5000) serves as a macromolecular initiator in the ring-opening polymerization of LA to obtain an amphiphilic diblock copolymer. This copolymer is used to prepare nanoparticles, forming an active drug delivery system. The nanoparticles encapsulate Triptolide , overcoming the poor water solubility of Triptolide and reducing its toxicity.
Formula:
(C2H4O)nC9H12N2O4
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