Pt-ttpy is a metallo-organic compound and an effective G-quadruplex ligand that efficiently induces significant telomere-associated DNA damage in cancer cells by inhibiting telomerase and/or telomere function. It also causes various chromatin abnormalities during mitosis, such as chromatin bridges, ultrafine bridges (UFB), and double-stranded breaks (DSB).
Molecular Weight:
589.38
CAS Number:
[727721-37-1]
Formula:
C22H17Cl2N3Pt
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