NH2-PEG6-Val-Cit-PAB-OH, CAS [[2055024-60-5]] Preis auf Anfrage

Product Overview

• Article Name: NH2-PEG6-Val-Cit-PAB-OH, CAS [[2055024-60-5]] Preis auf Anfrage
• Biozol Catalog Number: TGM-TYD-01891
• Supplier Catalog Number: TYD-01891
• Alternative Catalog Number: TGM-TYD-01891-10MG,TGM-TYD-01891-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

NH2-PEG6-Val-Cit-PAB-OH is a cleavable ADC linker composed of a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzyl alcohol on PAB is suitable for coupling with reactive groups (such as PNP) to facilitate binding with drug payloads. The primary amine enables versatile reactions, including coupling with carboxylic acids, reductive amination with ketones or aldehydes, and more specialized applications like SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide undergoes cleavage by intracellular proteases, allowing efficient payload delivery via an elimination mechanism within the PAB structure.

Product Properties

• Molecular Weight: 714.847
• CAS Number: [2055024-60-5]
• Formula: C33H58N6O11
• Target: ADC Linker

Images

TYD-01891