di-DTPA-LTL is a divalent hapten designed based on tyrosine-containing polypeptides. It exhibits excellent hydrophilicity and biodistribution properties. di-DTPA-LTL is labeled with 111In (indium) and 131I (iodine). By administering a fixed low dose (5 mg) of a bispecific antibody (anti-CEA x, anti-DTPA) and the di-DTPA hapten peptide (labeled with 111In) to patients, di-DTPA-LTL enables tumor radioimmunoimaging in patients with primary colorectal cancer expressing CEA.
Formula:
C52H82N12O23
Target:
Others
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