The compound 2-RIBOTAC-U recruiter-linker (Compound 9) is composed of an RNase L recruiter and a linker. It reacts via copper-catalyzed click chemistry with either 2-azido-uridine or 5-azidomethyl-uridine to form 2-RIBOTAC-U and 5-RIBOTAC-U, respectively. Notably, 2-RIBOTAC-U exhibits activity against SARS-CoV-2.
Formula:
C33H38N2O9S
Target:
Others
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