4E1rcat analogue 2 has an (E)-3-(2-furanmethyl methylene)-2-pyrrolidone core structure. Its analogue 4E1rcat blocked the interaction between ATG5-ATG16L1 and ATG5-TECAIR in the in vitro binding assay, with IC50 values of 1.1 µM and 1.7 µM respectively.
Molecular Weight:
497.54
Purity:
0.9795
Formula:
C33H23NO4
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