ATG5-PPI Inhibitor 27e has a core structure of (E)-3-(2-furfurylmethylene)-2-pyrrolidone, and it blocks the interactions between ATG5-ATG16L1 and ATG5-TECAIR in in vitro binding assays with IC50 values of >33 µM and 17.26 µM, respectively.
Molecular Weight:
481.93
Purity:
98.71%
Formula:
C29H20ClNO4
Target:
ATG
TYD-04697
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