ATG5-PPI Inhibitor 12d has an (E)-3-(2-furanmethyl methylene)-2-pyrrolidone core structure. In in vitro binding experiments, it blocked the interactions between ATG5-ATG16L1 and ATG5-TECAIR, with IC50 values of >100 µM and 17.5 µM, respectively.
Molecular Weight:
430.41
CAS Number:
[2841473-81-0]
Formula:
C24H18N2O6
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