Brazil Variant, Brazilian lineage, N501Y mutation of SARS-CoV-2 Spike, SARS-CoV-2, coronavirus, SARS-CoV-2 spike RBD, SARS-CoV-2 spike protein, 2019-nCoV, COVID-2019, COVID-19, RBD (N501Y), 501.V2, VUI-202012/01, B.1.1.7, B117, UK Variant, UK lineage, B.
The spike (S) glycoprotein of coronaviruses is essential for binding of the virus to the host cell at the beginning of the infection process. The target protein is also a major immunogen and a possible target for entry inhibitors. The SARS-CoV-2 spike (S