Nocodazole is a microtubule inhibitor which reversibly binds tubulin and alters tubulin-associated GTP hydrolysis as well as microtubule dynamics. While nocodazole is used to study many aspects on microtubule function, it is most commonly used to synchronize cell cycling in culture. Nocodazole is also used to induce the formation of Golgi ministacks in eukaryotic cells.
