Ac-PAL-AMC is a fluorogenic substrate of the caspase-like activity of the proteasome. It is preferentially cleaved by immunoproteasomes compared to constitutive proteasomes. The AMC fluorescence can be detected by a fluorimeter or a plate reader using excitation/emission wavelengths at 360 nm/460 nm, respectively. This substrate can be used to determine the caspase-like activity of immunoproteasomes. Working concentration is 50 - 200 µM.
Molecular Weight:
498.6 g/mol
Buffer:
powder, no buffer
Source:
chemical synthesis
* VAT and and shipping costs not included. Errors and price changes excepted
