4E Binding Protein 1, phosphorylated (Thr70) (Protein Synthesis Initiation Factor 4E Binding Protein, eIF-4EBP1, PHAS-1, PHAS-I, Eukaryotic Translation Initiation Factor BP), Rabbit

Product Overview

• Article Name: 4E Binding Protein 1, phosphorylated (Thr70) (Protein Synthesis Initiation Factor 4E Binding Protein, eIF-4EBP1, PHAS-1, PHAS-I, Eukaryotic Translation Initiation Factor BP), Rabbit
• Biozol Catalog Number: USB-0004-20A
• Supplier Catalog Number: 0004-20A
• Alternative Catalog Number: USB-0004-20A-100
• Manufacturer: US Biological
• Host: Rabbit
• Category: Antikörper
• Application: IP, WB
• Immunogen: Synthetic phosphopeptide derived from the sequence of mouse 4E-BP1.

Product Description

4E-BP1 (also known as PHAS-1) normally binds eIF4E, inhibiting cap-dependent translation. Hyperphosphorylation of 4E-BP1 disrupts this binding, activating cap-dependent translation. The PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1. 4E-BP1

Product Properties

• UniProt: Q13541
• Purity: Purified by Protein A affinity chromatography.
• Form: Supplied as a liquid in 10mM HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol. No preservative added.