N-terminal fragment of human 14-3-3 gamma where the N-terminal Val was acetylated
14-3-3 proteins are present as multigene families in most organisms. Signal-induced phosphorylation has the ability to change protein function. Sometimes, however, phosphorylation is not enough to change a proteins function. 14-3-3 proteins play an important role of bringing signal transduction to completion. They regulate many cellular processes that are important in cancer biology, such as apoptosis and cell-cycle checkpoints. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:3,000. Detects a band of ~ 33kD. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clonality:
Monoclonal
Clone Designation:
[KC21]
Isotype:
IgG2a
Purity:
Mouse ascites
Form:
Supplied as a liquid. May contain azide. See Certificate of Analysis.
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