14-3-3, gamma, NT (Protein Kinase C Inhibitor Protein 1, KCIP-1, 14-3-3 Protein gamma, N-terminally Processed, YWHAG), Rabbit
Biozol Catalog Number:
USB-0014-08B
Supplier Catalog Number:
0014-08B
Alternative Catalog Number:
USB-0014-08B-200
Manufacturer:
US Biological
Host:
Rabbit
Category:
Antikörper
Application:
ELISA, FC, IHC, WB
Immunogen:
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 63-92 in the N-terminal region of human 14-3-3, gamma. Species sequence homology: bovine, chicken, Xenopus, Zebrafish
YWHAG belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. Applications: Suitable for use in Indirect Flow Cytometry, Immunohistochemistry, ELISA and Western Blot. Other applications have not tested. Recommended Dilution: Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.