Methyl donor, cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury. Synonyms: 5-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5-deoxyadenosine Disulfate, 5-[(L-3-Amino-3-carboxypropyl)methylsulfonio]-5-deoxyadenosine Disulfate, S-Adenosylmethionine Disulfate, Active Methionine Disulfate, Ademetionine Disulfate, L-S-Adenosylmethionin Disulfate, S-Adenosyl-L-methionine Disulfate CAS No: Free Acid: 979-92-0 Chloride: 24346-00-7 Molecular Formula: C15H26N6O13S Molecular Weight: 594.59 Appearance: Off-white to light brown solid Purity: 95% Melting Point: >103C (subl.) TLC Conditions: C18, Methanol : Water : Acetic Acid = 5 : 5 : 0.1, Visualized with UV and KMnO4, Single Spot, Rf = 0.40 Elemental Analysis (Theoretical): %C: 30.30, %H: 4.41, %N: 14.13 Solubility: Methanol (Very Slightly, Heated), Water (Slightly) Storage and Stability: Store at -20C. Hygroscopic. Under Inert Atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
594.59
Purity:
95%
Form:
Off-white to light brown solid
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