| Alamethicin is a peptide antibiotic, produced by the fungus Trichoderma viride. Alamethicin contains the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib), which strongly induces helical peptide structures. In cell membranes, it forms voltage-dependent ion channels by aggregation of four to six molecules. Synonyms: (3S,12R)-1-((S)-1-((6S,12S,15S,21S,30S)-1-((R)-1-(2-Acetamido-2- methylpropanoyl)pyrrolidin-2-yl)-15-(3-amino-3-oxopropyl)-30-isobutyl-21-isopropyl- 3,3,6,9,9,2,18,18,24,24,33,33-dodecamethyl-1,4,7,10,13,16,19,22,25,28,31- undecaoxo-2,5,8,11,14,17,20,23,26,29,32-undecaazatetratriacontan-34- oyl)pyrrolidin-2-yl)-12-(((R)-5-amino-1-(((S)-1-hydroxy-3-phenylpropan-2-yl)amino)-1, 5-dioxopentan-2-yl)carbamoyl)-3-isopropyl-6,6,9,9-tetramethyl-1,4,7,10-tetraoxo-2,5, 8,11-tetraazapentadecan-15-oic Acid CAS No: 27061-78-5 Molecular Formula: C92H150N22O25 Molecular Weight: 1964.31 Form: Supplied as an off-white to brown crystalline. Purity: 90% Melting Point: >172C (dec.) Solubility: DMSO (Slightly ,Heated), Methanol (Slightly) Storage and Stability: May be stored at -20C. Stable for 6 months after receipt at -20C. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures. |
