(R)-tert-Butylsulfinamide is a chiral ligand used in pharmaceutical compositions. (R)-tert-Butylsulfinamide can be readily transformed into P,N-sulfinyl imine ligands through condensation with aldehydes and ketones, which can undergo iridium-catalyzed asymmetric hydrogenation of olefins. (R)-(+)-2-Methyl-2-propanesulfinamide may be used to prepare N-(1-cyclohexylmethylidene)-2-methylpropane-2-sulfinamide via copper mediated condensation with cyclohexane carboxaldehyde. It may also be used to prepare (20E)-N-[t-butyl-(R)-sulfinyl]-3beta-(t-butyldimethylsilyloxy)-pregn-5-en-20-imine, an intermediate for the development of androgen receptor antagonists. Synonyms: (R)-(+)-2-Methyl-2-propanesulfinamide, (R)-N-tert-Butanesulfinamide, (R)-tert-Butanesulfinamide, (R)-(+)-t-Butyl sulfinamide CAS No: 196929-78-9 Molecular Formula: C4H11NOS Molecular Weight: 121.2 Appearance: Off-white to yellow solid Purity: 97% Melting Point: 103-107C (lit.) Solubility: Chloroform Storage: 4C
Molecular Weight:
121.2
Purity:
97%
Form:
Off-white to yellow solid
CAS Number:
[196929-78-9]
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