A selective, non-peptide antagonist of corticotropin releasing factor receptors (CRF1). It blocks CRF-induced adenylate cyclase activation and attenuates activation of the HPA axis by CRF. It displayed anxiolytic-like activity in the rat elevated plus-maze test, brain penetrant. Form: Pale Yellow Solid Melting Point: 167-169C Solubility: DMSO, Methanol Pfizer Compound
Molecular Weight:
400.99
Form:
Pale Yellow Solid
CAS Number:
[257639-98-8]
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