Crenolanib, CAS [[670220-88-9]]

Product Overview

• Article Name: Crenolanib, CAS [[670220-88-9]]
• Biozol Catalog Number: USB-007102
• Supplier Catalog Number: 007102
• Alternative Catalog Number: USB-007102-5
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Crenolanib is a tyrosine kinase inhibitor that acts by specifically inhibiting the receptor tyrosine kinases PDGFRalpha and PDGFRbeta. Crenolanib inhibits the activity of PDGFRalpha D842V kinase and prevented the phosphorylation of wild type PDGFRalpha. Crenolanib possesses potential antineoplastic activity. Crenolanib is believed to suppress PDGFR-related signal transduction pathways leading to the inhibition of tumor angiogenesis and tumor cell proliferation. Form: White to Off-White Solid Melting Point: 217-220C Solubility: DMSO, Methanol

Product Properties

• Molecular Weight: 443.54
• Form: White to Off-White Solid
• CAS Number: [670220-88-9]