An oxidative metabolite of Dasatinib (M5 metabolite). Dasatinib N-oxide is a major metabolite of the Abl and Src kinase inhibitor dasatinib and a potential impurity in commercial preparations of dasatinib. Synonyms: N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide N-Oxide CAS No: 910297-52-8 Molecular Formula: C22H26ClN7O3S Molecular Weight: 504 Appearance: Off-white to pale yellow solid Purity: 95% (HPLC) (Typically 99%) NMR, MS: Conforms to reference Melting Point: 193-195C Elemental Analysis: %C: 47.20, %H: 5.91, %N: 17.30 Solubility: Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
504
Purity:
95% (HPLC) (Typically 99%)
Form:
Off-white to pale yellow solid
CAS Number:
[910297-52-8]
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