An N-Hydroxyguanidine prodrug and intermediate in the preparation of Melagatran. Synonyms: N-[(1R)-1-Cyclohexyl-2-[(2S)-2-[[[[4-[(hydroxyamino)iminomethyl]phenyl]methyl]amino]carbonyl]-1-azetidinyl]-2-oxoethyl]glycine, Melagatran Hydroxyamidine CAS No: 192939-72-3 Molecular Formula: C22H31N5O5 Molecular Weight: 445.51 Purity: 95% Appearance: White to off-white solid Melting Point: >185C (dec.) Solubility: DMSO (Very Slightly, Heated) Method for Determining Identity: Proton NMR and Mass Spectrometric Analysis TLC Conditions: C18, Acetonitrile: Water: Ammonium Hydroxide=8:2:02, Visualized with UV and KMnO4, Sigle spot, Rf=0.65 Elemental Analysis: Calculated: %C: 59.31, %H: 7.01, %N: 15.72 Atmosphere: Inert Storage and Stability: Store at -20C. Caution: Hygroscopic, Store under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap
Molecular Weight:
445.51
CAS Number:
[192939-72-3]
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