| Mitragynine is an indole alkaloid from the plant M. speciosa. It has stimulatory, antinociceptive, and opiate-like effects, acting through noradrenergic, serotonergic, and opioid receptors.1,2 Mitragynine has a higher affinity for the µ-opioid receptor than the delta- or kappa-opioid receptors (pKi = 8.14, 7.22, and 5.96, respectively).2 Mitragynine and its derivatives have been identified in products sold as incense.3 The identification and quantification of mitragynine and related alkaloids, as well as their phase I and II metabolites, have been described.4-6 This product is intended for forensic applications. This product is qualified as a Reference Material that has been manufactured and tested to ISO/IEC 17025 and ISO 17034 international standards. Synonyms: (alphaE,2S,3S,12bS)-3-Ethyl-1,2,3,4,6,7,12,12b-octahydro-8-methoxy-alpha-(methoxymethylene)-indolo[2,3-a]quinolizine-2-acetic Acid Methyl Ester, (-)-Mitragynine, 9-Methoxy-corynantheidine, 16,17-Didehydro-9,17-dimethoxy-corynan-16-carboxylic Acid Methyl Ester CAS No: 4098-40-2 Molecular Formula: C23H30N2O4 Molecular Weight: 398.5 Appearance: Light orange to dark beige to very dark yellow solid Purity: 98% Melting Point: >90C (dec.) Solubility: Chloroform (Slightly), Methanol (Slightly) Storage: -20C |
