PF 184 is a potent and selective IKK-2 inhibitor (IC50 = 37 nM). Displays selectivity over 85 other kinases. Inhibits IL-1beta-induced TNF-alpha in a steroid-insensitive in vitro model of oxidative stress. Pfizer Compound
Molecular Weight:
619.09
CAS Number:
[1187460-81-6]
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