Selective checkpoint kinase 1 (Chk1) inhibitor (Ki values are 0.49 and 47 nM for Chk1 and Chk2 respectively). Abrogates cell cycle arrest at S and G2-M checkpoints, sensitizes cells to DNA damage. Synonyms: (alphaR)-alpha-Amino-N-[5,6-dihydro-2-(1-methyl-1H-pyrazol-4-yl)-6-oxo-1H-pyrrolo[4,3,2-ef][2,3]benzodiazepin-8-yl]cyclohexaneacetamide CAS Number: 952021-60-2 Molecular Weight: 419.48 Molecular Formula: C22H25N7O2 Storage and Stability: Store at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Pfizer Compound
Molecular Weight:
419.48
CAS Number:
[952021-60-2]
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