PF-4708671 is a highly specific inhibitor of p70 ribosomal S6 kinase (S6K1). PF-4708671 inhibits S6K1-mediated phosphorylation of S6 protein in response to IGF-1 (insulin-like growth factor 1), while having no effect on highly related RSK (p90 ribosomal S6 kinase) and MSK (mitogen- and stress-activated kinase) kinases. Form: Pale purple Solid Melting Point: 189-191C Solubility: DMSO, Methanol Pfizer Compound
Molecular Weight:
390.41
Form:
Pale purple Solid
CAS Number:
[1255517-76-0]
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