Sumanirole is a high affinity D2 receptor agonist (EC50 values are between 17 and 75 nM in cell-based assays). Sumanirole displays >200-fold selectivity for the D2 receptor against other dopamine receptor subtypes (Ki values are 9.0, 1940, >2190 and >7140 for D2, D3, D4 and D1 receptors respectively). Sumanirole exhibits anti-Parkinsonian activity similar to Ropinirole. Form: Off-White to Light Beige Solid Melting Point: 206-208C (dec.) Solubility: DMSO, Methanol Pfizer Compound
Molecular Weight:
319.31
Form:
Off-White to Light Beige Solid
CAS Number:
[179386-43-7]
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