Taspine is an alkaloid isolated from Radix et Rhizoma Leonticis. It shows various pharmaceutical properties: bacteriostatic, wound healing, cytotoxicity, immunosuppression, acetilcholinesterase inhibition, and inhibition of the activity of tumor angiogenesis. Used as human acid beta-glucosidase inhibitor and for the treatment of Gaucher disease. Appearance: Supplied as an off-white to pale yellow solid. Purity 90% Melting Point: >300C (dec.) Solubility: Chloroform Method for Determining Identity: Proton NMR (CDCl3) Spectroscopic and Mass Spectrometric Analysis TLC Conditions: SiO2, Dichloromethane: Methanol: Ammonium Hydroxide = 8: 2: 0.1, Visualized with UV and KMnO4, Rf=0.50 Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
369.37
Purity:
~90%
Form:
Supplied as an off-white to pale yellow solid.
CAS Number:
[602-07-3]
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