Thiocolchicoside (BRN 0072205, NSC 147755, Coltramyl, 10-thio-Colchicoside, 2-Demethoxy-2-glucosidoxythiocolchicine), CAS [[602-41-5]]
Biozol Catalog Number:
USB-021740
Supplier Catalog Number:
021740
Alternative Catalog Number:
USB-021740-50
Manufacturer:
US Biological
Category:
Molekularbiologie
Potent competitive gamma-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist. Weak nicotinic acetylcholine receptor agonist. Muscle relaxant. Anti-inflammatory. Has analgesic properties. Shows strong epileptogenic and convulsant activity. Anticancer compound through inhibition of NF-kappaB and NF-kappaB-regulated gene products Apoptosis inducer. Suppressed osteoclastogenesis induced by RANKL and tumor cells via the NF-kappaB signaling pathway. Therapeutic option for the management of bone metastatic disease. Form: Yellow solid Melting Point: 190-198C Solubility: Water Storage and Stability: Short-term Storage: +4C Long-term Storage: -20C Stable for at least 2 years after receipt when stored at -20C.
Molecular Weight:
563.62
Form:
Yellow solid
CAS Number:
[602-41-5]
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