Torin 1 is a potent and selective mTOR inhibitor (IC50 = 2-10nM for mTORC1 and mTORC2). Displays 200-fold selectivity for mTOR over DNA-PK, ATM and hVps34. Synonyms: 1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h]-1,6-naphthyridin-2(1H)-one CAS No: 1222998-36-8 Molecular Formula: C35H28F3N5O2 Molecular Weight: 607.62 Solubility: Chloroform, DMSO, Methanol (Sparingly) Form: Supplied as a white to off-white solid. Purity: As Reported Melting Point: >223C (dec.) Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Pfizer Compound
Molecular Weight:
607.62
Form:
Supplied as a white to off-white solid.
CAS Number:
[1222998-36-8]
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