Glyptins are class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic. Synonyms: (2S)-1-[2-[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile, LAF 237, NVP-LAF 237, Galvus CAS No: 274901-16-5 Molecular Formula: C17H25N3O2 Molecular Weight: 303.4 Appearance: White to off-white solid Purity: 97% Melting Point: >145C (dec.) Solubility: DMF: 20mg/ml, DMSO: 15mg/ml, Ethanol: 15mg/ml, PBS (pH 7.2): 10mg/ml Storage and Stability: May be stored at RT for short-term only. Hygroscopic. Under inert atmosphere. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
303.4
Purity:
97%
Form:
White to off-white solid
CAS Number:
[274901-16-5]
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