ERV3, CT (ERV3-1, ERV3, HERV-R_7q21.2 provirus ancestral Env polyprotein, ERV-3 envelope protein, ERV3-1 envelope protein, Envelope polyprotein, HERV-R envelope protein, Surface protein, Transmembrane protein), Rabbit

Catalog Number: USB-035223
Article Name: ERV3, CT (ERV3-1, ERV3, HERV-R_7q21.2 provirus ancestral Env polyprotein, ERV-3 envelope protein, ERV3-1 envelope protein, Envelope polyprotein, HERV-R envelope protein, Surface protein, Transmembrane protein), Rabbit
Biozol Catalog Number: USB-035223
Supplier Catalog Number: 035223
Alternative Catalog Number: USB-035223-200
Manufacturer: US Biological
Host: Rabbit
Category: Antikörper
Application: ELISA, IHC, WB
Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 445-474 in the C-terminal region of human ERV3.
The human genome includes many retroelements including the human endogenous retroviruses (HERVs). ERV3, one of the most studied HERVs, is thought to have integrated 30 to 40 million years ago and is present in higher primates with the exception of gorillas. Taken together, the observation of genome conservation, the detection of transcript expression, and the presence of conserved ORFs is circumstantial evidence for a functional role. A functional role is also suggested by the observation that downregulation of ERV3 is reported in choriocarcinoma. [provided by RefSeq]. Applications: Suitable for use in Immunohistochemistry, Western Blot and ELISA. Other applications have not been tested. Recommended Dilutions: Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
NCBI: 001007254
UniProt: Q14264
Purity: Purified by Protein A and peptide affinity chromatography.
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.