Ptk2, ID (Ptk2, Fadk, Fak, Fak1, Kiaa4203, Focal adhesion kinase 1, Focal adhesion kinase-related nonkinase, Protein-tyrosine kinase 2, p125FAK, pp125FAK), Rabbit

Product Overview

• Article Name: Ptk2, ID (Ptk2, Fadk, Fak, Fak1, Kiaa4203, Focal adhesion kinase 1, Focal adhesion kinase-related nonkinase, Protein-tyrosine kinase 2, p125FAK, pp125FAK), Rabbit
• Biozol Catalog Number: USB-040636
• Supplier Catalog Number: 040636
• Alternative Catalog Number: USB-040636-200
• Manufacturer: US Biological
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Immunogen: Mouse Ptk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 425-453 amino acids from the Central region of Mouse Ptk2.

Product Description

Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly (By similarity). Plays a potential role in oncogenic transformations resulting in increased kinase activity. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Product Properties

• NCBI: 032008
• UniProt: P34152
• Purity: Purified by Protein A affinity chromatography.
• Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.