Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor. Anti-tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM). GSK-3beta (glycogen synthase kinase-3beta) inhibitor. Apoptosis inhibitor. Apoptosis inducer. Angiogenesis inhibitor. Synonyms: 9-Nitro-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5H)-one CAS Number: 237430-03-4 Molecular Weight: 293.3 Molecular Formula: C16H11N3O3 Solubility: DMSO, insoluble in water or 100% ethanol. Appearance: Supplied as a yellow to brown powder. Purity: 98% (NMR) Storage and Stability: Store at 4C. Caution: Light-sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
293.3
Purity:
98% (NMR)
Form:
Supplied as a yellow to brown powder.
CAS Number:
[237430-03-4]
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