BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. Its downstream signaling is dependent on NF-kappaB and JNK. Human, mouse, HEK 293 cells. The extracellular domain of mouse BCMA (aa1-46) is fused at theC-terminus to the Flow Cytometry portion of human IgG1. Biological Activity: Blocks the binding of mouse BAFF and human APRIL to their receptors BCMA and TACI. Specificity: Binds mouse and human BAFF and APRIL. Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight:
35
Purity:
~95% (SDS-PAGE). Endotoxin: 0.01EU/ug (LAL)
Form:
Supplied as a lyophilized powder from PBS. Reconstitute with 50ul sterile ddH2O.
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