Cell permeable, potent, selective, non-transition state and non-competitive gamma-secretase inhibitor. Notch processing inhibitor. Only weakly affects presenilinase activity. Synonyms: gamma-Secretase Inhibitor XXI, (2S)-2-([(3,5-Difluorophenyl)acetyl]amino)-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide CAS No: 209986-17-4 Molecular Formula: C27H24F2N4O3 Molecular Weight: 490.5 Appearance: White to off-white solid Purity: 98% (HPLC) 1H-NMR: Conforms to reference Solubility: DMSO Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
490.5
Purity:
98% (HPLC)
Form:
White to off-white solid
CAS Number:
[209986-17-4]
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