IBMX (3-Isobutyl 1-methylxanthine, NSC 165960, SC2964, EINECS 249-259-3), CAS [[28822-58-4]]
Biozol Catalog Number:
USB-044890
Supplier Catalog Number:
044890
Alternative Catalog Number:
USB-044890-500,USB-044890-1
Manufacturer:
US Biological
Category:
Biochemikalien
Cell permeable, competitive, non-specific cAMP and cGMP phosphodiesterase inhibitor. Increases cAMP levels that activate PKA, leading to decreased proliferation, increased differentiation and induction of apoptosis. Enhances differentiation of 3T3-L1 cells. Non-selective adenosine receptor antagonist. Inhibits Ca2+ ion channels. Activates TNF-alpha. Adipogenic. Activates leukotriene synthesis. Reduces inflammation and innate immunity. IC50 values are 13, 18, 19, 32 and 50uM for PDE4, PDE3, PDE1, PDE5 and PDE2 respectively Solubility: DMSO, Dichloromethane, Ether, Ethyl acetate, Methanol and ethanol. Insoluble in water. Storage and Stability: Short-term Storage: +4C Long-term Storage: -20C Stable for at least 2 years after receipt when stored at -20C.
Molecular Weight:
222.3
Purity:
99% (HPLC)
Form:
Supplied as a white solid.
CAS Number:
[28822-58-4]
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