Induces neuritogenesis. Potent and selective irreversible proteasome inhibitor. Specifically inhibits 20S proteasome (MCP, multicatalytic complex). Blocks proteasome activity by targeting the catalytic beta-subunit. Apoptosis inducer. Anticancer compound. Upregulates HSP70 and HSP22. Induces differentiation and inhibits cell cycle progression in several tumor cell lines. Inhibits NF-kappaB activation by inhibiting IkappaB degradation. Cathepsin A inhibitor. gamma-Secretase activity inhibitor. Anti-adipogenic. Source: Streptomyces lactacystinnaeus strain OM-6519 CAS Number: 133343-34-7 Molecular Weight: 376.4 Molecular Formula: C15H24N2O7S Solubility: Water, methanol, ethanol, DMSO, pyridine, acetonitrile or dimethyl formamide. Insoluble in hexane, benzene, chloroform or ethyl acetate. Appearance: Supplied as a white to off-white solid. Purity: 98% (HPLC) Storage and Stability: Store at -20C. Caution: Light-sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
376.4
Purity:
98% (HPLC)
Form:
Supplied as a white to off-white solid.
CAS Number:
[133343-34-7]
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