Potent and highly selective, irreversible inhibitor of soluble guanylyl cyclase (sGC). The binding is competitive with nitric oxide (NO). Tool to elucidate the nitric oxide (NO)-cGMP pathway. Apoptosis inhibitor Inhibits growth and migration of prostate cancer cells independent of its effects on GMP levels. Synonyms: 1H-[1,2,4]Oxadiazole[4,3-a]quinoxalin-1-one CAS Number: 41443-28-1 Molecular Weight: 187.2 Molecular Formula: C9H5N3O2 Solubility: DMSO (5mg/ml), ethyl acetate or 100% ethanol (1.2mg/ml), insoluble in water Appearance: Supplied as a white to pale yellow solid. Purity: 98% (NMR) Storage and Stability: For short term, store at 4C. For long term, store at -20C in the dark. Solutions may decompose slowly. Protect from light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
187.2
Purity:
98% (NMR)
Form:
Supplied as a white to pale yellow solid.
CAS Number:
[41443-28-1]
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