PD 184,352 (2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide, CI-1040), CAS [[212631-79-3]]

Product Overview

• Article Name: PD 184,352 (2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide, CI-1040), CAS [[212631-79-3]]
• Biozol Catalog Number: USB-045129
• Supplier Catalog Number: 045129
• Alternative Catalog Number: USB-045129-1,USB-045129-5
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

MEK (MAPKK) inhibitor. Potent and selective MAPK (ERK kinase 1, MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo). Suppresses activation of MAPK but does not block its activity. Antiproliferative. Causes cell-cycle arrest in G1 phase. Tumor suppressor. Apoptosis inducer. Synonyms: 2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide, CI-1040 CAS Number: 212631-79-3 Molecular Formula: C17H14ClF2IN2O2 Molecular Weight: 478.7 Solubility: DMSO Method for Determining Identity: Proton NMR Appearance: White to off-white solid. Purity: 95% (HPLC, NMR) Storage and Stability: Store at -20C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 478.7
• Purity: 95% (HPLC, NMR)
• Form: White to off-white solid.
• CAS Number: [212631-79-3]