Highly selective, reversible and cell permeable MEK (MAP kinase kinase) inhibitor. Blocks the phosphorylation and activation of the MAP kinase pathway. T cell activation inhibitor. Inhibits cell growth and cell proliferation of several cancer cells. Synonyms: 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one, 2-(2-amino-3-methoxyphenyl)oxanaphthalen-4-one, NSC 679828, PD 098059 CAS Number: 167869-21-8 Molecular Formula: C16H13NO3 Molecular Weight: 267.3 Solubility: Anhydrous DMSO, methanol or dichloromethane. Slightly soluble in ethanol. Appearance: Supplied as a yellow solid. Purity: 98% (NMR) Storage and Stability: Store at 4C for short term storage. Caution: Light-sensitive. Store solutions at -20C in the dark. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
267.3
Purity:
98% (NMR)
Form:
Supplied as a yellow solid.
CAS Number:
[167869-21-8]
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