Sirtuin 1 (IntraCellular) BioAssay(TM) ELISA Kit (Human) (Sirt01, SIR02 like Protein 01)
Biozol Catalog Number:
USB-045285
Supplier Catalog Number:
045285
Alternative Catalog Number:
USB-045285-96
Manufacturer:
US Biological
Category:
Kits/Assays
Sirtuins (Silent information regulators, SIRTs) deacetylate and/or ADP-ribosylate lysine residues of target proteins in an NAD+-dependent manner. Sirtuins are critical regulators of many cellular processes, including insulin secretion, the cell cycle and apoptosis. Sirtuins, in particular SIRT1, emerged as critical regulators of longevity and aging in several model organisms. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimers disease are associated with sirtuins. SIRT1 has been suggested as potential biomarker for tumorigenesis. Storage and Stability: Short-term Storage: +4C Long-term Storage: +4C
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