Selective inhibitor of Pim-1 and Pim-2 protein kinases. Inducer of G1 phase cell cycle arrest. Inducer of p27Kip1. Inducer of apoptosis through the mitochondrial pathway. Inhibitor of the mammalian target of rapamycin C1 (mTORC1) pathway. Downregulates c-myc. Inhibitor of PRAS40 phosphorylation and mTOR activity. Potential anti-cancer compound. Blocks prostate cancer growth. Synonyms: (5E/Z)-[[3-(Trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione CAS Number: 327033-36-3 Molecular Weight: 273.2 Molecular Formula: C11H6F3NO2S Method for Determining Identity: Proton NMR Solubility: DMSO (5mg/ml). Appearance: Supplied as a white to off-white solid. Purity: 95% (NMR) Storage and Stability: For short term storage, store at 4C. Stable for 1 year after receipt when stored at -20C. Protect from light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
273.2
Purity:
95% (NMR)
Form:
Supplied as a white to off-white solid.
CAS Number:
[327033-36-3]
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