Antimitotic alkaloid. Tubulin polymerization and microtubule assembly inhibitor. Axonal cytoskeleton modulator. Apoptosis inducer. Thiocolchicine-dimers were shown to be potent topoisomerase I inhibitors. Synonyms: 10-Demethoxy-10-methylthiocolchicine, NSC 186301 CAS Number: 2730-71-4 Source: Semi-synthetic Molecular Weight: 415.5 Molecular Formula: C22H25NO5S Solubility: Ethanol or acetone. Almost insoluble in water or ether. Appearance: Supplied as a yellow solid. Purity: 95% (NMR) Storage and Stability: Store at 4C. Caution: Light-sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
415.5
Purity:
95% (NMR)
Form:
Supplied as a yellow solid.
CAS Number:
[2730-71-4]
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